Disease that occurs in 1 in 100,000 live births whose symptoms include loss of body strength, wrinkles, gray hair, hair loss, cataracts, osteoporosis, and heart problems and mimic the effects of aging. Life expectancy is 46 years1.

1. PhD, D. A. S. & LaPlante, M. D. Lifespan: Why We Age and Why We Don’t Have To. (Atria Books, New York, 2019).