The Great Lakes region is considered a likely climate change haven based on its supply of fresh water and relative shelter from Sea change, fires, and hurricanes.
San Diego to Great Lakes region: Detroit (4:30 hrs) Chicago (4:15 hr) Cleveland (4:15 hrs) Minneapolis (3:51 hrs) (MSP)
Duluth, MN: From Chicago ~7 hours by car From SAN 6h2mins via MSP